The role of stress in autoimmune disorders
Order ID |
53563633773 |
Type |
Essay |
Writer Level |
Masters |
Style |
APA |
Sources/References |
4 |
Perfect Number of Pages to Order |
5-10 Pages |
Description/Paper Instructions
The role of stress in autoimmune disorders
Autoimmune disorders occur when the immune system mistakenly attacks healthy cells and tissues in the body, leading to chronic inflammation and tissue damage. While the exact causes of autoimmune disorders are not fully understood, it is believed that a combination of genetic, environmental, and lifestyle factors play a role. Stress is one such environmental factor that has been shown to play a significant role in the development and exacerbation of autoimmune disorders.
Stress can affect the immune system in several ways. One of the primary ways that stress affects the immune system is by increasing the production of cortisol, a stress hormone. Cortisol has both anti-inflammatory and immunosuppressive effects on the body, which can lead to a weakening of the immune system over time. This can make the body more susceptible to infections and other health problems, including autoimmune disorders.
In addition to cortisol, stress can also cause the body to produce other inflammatory molecules, such as cytokines and chemokines. These molecules can contribute to chronic inflammation, which is a key factor in the development and progression of autoimmune disorders.
Stress can also have a direct impact on the function of immune cells, including T cells and B cells, which are responsible for identifying and attacking foreign invaders in the body. Chronic stress can lead to a reduction in the number and function of these immune cells, which can further weaken the immune system and increase the risk of developing autoimmune disorders.
Furthermore, stress can also contribute to the breakdown of the intestinal barrier, leading to increased intestinal permeability, also known as “leaky gut”. This can allow harmful substances such as bacteria and toxins to enter the bloodstream, triggering an immune response and leading to chronic inflammation and autoimmune disorders.
There is growing evidence to suggest that stress may play a role in the development and exacerbation of several autoimmune disorders, including rheumatoid arthritis, lupus, multiple sclerosis, and inflammatory bowel disease. For example, studies have shown that individuals with higher levels of stress are more likely to develop rheumatoid arthritis and experience more severe symptoms of the disease. Similarly, stress has been linked to an increased risk of developing multiple sclerosis and a worsening of symptoms in those who already have the condition.
In addition to increasing the risk of developing autoimmune disorders, stress can also exacerbate symptoms in those who already have the condition. Stress has been shown to increase disease activity and symptom severity in individuals with autoimmune disorders, leading to an overall decrease in quality of life.
Fortunately, there are several strategies that can be used to manage stress and reduce its negative impact on the immune system and autoimmune disorders. These strategies include relaxation techniques such as meditation, deep breathing, and yoga, as well as regular exercise and a healthy diet. In addition, seeking professional support such as counseling or therapy can also be helpful in managing stress.
In conclusion, stress is a significant environmental factor that plays a role in the development and exacerbation of autoimmune disorders. Stress can weaken the immune system, trigger chronic inflammation, and lead to the breakdown of the intestinal barrier, all of which can contribute to the development and progression of autoimmune disorders. By taking steps to manage stress, individuals with autoimmune disorders can reduce their risk of developing complications and improve their overall quality of life.
RUBRIC
QUALITY OF RESPONSE |
NO RESPONSE |
POOR / UNSATISFACTORY |
SATISFACTORY |
GOOD |
EXCELLENT |
Content (worth a maximum of 50% of the total points) |
Zero points: Student failed to submit the final paper. |
20 points out of 50: The essay illustrates poor understanding of the relevant material by failing to address or incorrectly addressing the relevant content; failing to identify or inaccurately explaining/defining key concepts/ideas; ignoring or incorrectly explaining key points/claims and the reasoning behind them; and/or incorrectly or inappropriately using terminology; and elements of the response are lacking. |
30 points out of 50: The essay illustrates a rudimentary understanding of the relevant material by mentioning but not full explaining the relevant content; identifying some of the key concepts/ideas though failing to fully or accurately explain many of them; using terminology, though sometimes inaccurately or inappropriately; and/or incorporating some key claims/points but failing to explain the reasoning behind them or doing so inaccurately. Elements of the required response may also be lacking. |
40 points out of 50: The essay illustrates solid understanding of the relevant material by correctly addressing most of the relevant content; identifying and explaining most of the key concepts/ideas; using correct terminology; explaining the reasoning behind most of the key points/claims; and/or where necessary or useful, substantiating some points with accurate examples. The answer is complete. |
50 points: The essay illustrates exemplary understanding of the relevant material by thoroughly and correctly addressing the relevant content; identifying and explaining all of the key concepts/ideas; using correct terminology explaining the reasoning behind key points/claims and substantiating, as necessary/useful, points with several accurate and illuminating examples. No aspects of the required answer are missing. |
Use of Sources (worth a maximum of 20% of the total points). |
Zero points: Student failed to include citations and/or references. Or the student failed to submit a final paper. |
5 out 20 points: Sources are seldom cited to support statements and/or format of citations are not recognizable as APA 6th Edition format. There are major errors in the formation of the references and citations. And/or there is a major reliance on highly questionable. The Student fails to provide an adequate synthesis of research collected for the paper. |
10 out 20 points: References to scholarly sources are occasionally given; many statements seem unsubstantiated. Frequent errors in APA 6th Edition format, leaving the reader confused about the source of the information. There are significant errors of the formation in the references and citations. And/or there is a significant use of highly questionable sources. |
15 out 20 points: Credible Scholarly sources are used effectively support claims and are, for the most part, clear and fairly represented. APA 6th Edition is used with only a few minor errors. There are minor errors in reference and/or citations. And/or there is some use of questionable sources. |
20 points: Credible scholarly sources are used to give compelling evidence to support claims and are clearly and fairly represented. APA 6th Edition format is used accurately and consistently. The student uses above the maximum required references in the development of the assignment. |
Grammar (worth maximum of 20% of total points) |
Zero points: Student failed to submit the final paper. |
5 points out of 20: The paper does not communicate ideas/points clearly due to inappropriate use of terminology and vague language; thoughts and sentences are disjointed or incomprehensible; organization lacking; and/or numerous grammatical, spelling/punctuation errors |
10 points out 20: The paper is often unclear and difficult to follow due to some inappropriate terminology and/or vague language; ideas may be fragmented, wandering and/or repetitive; poor organization; and/or some grammatical, spelling, punctuation errors |
15 points out of 20: The paper is mostly clear as a result of appropriate use of terminology and minimal vagueness; no tangents and no repetition; fairly good organization; almost perfect grammar, spelling, punctuation, and word usage. |
20 points: The paper is clear, concise, and a pleasure to read as a result of appropriate and precise use of terminology; total coherence of thoughts and presentation and logical organization; and the essay is error free. |
Structure of the Paper (worth 10% of total points) |
Zero points: Student failed to submit the final paper. |
3 points out of 10: Student needs to develop better formatting skills. The paper omits significant structural elements required for and APA 6th edition paper. Formatting of the paper has major flaws. The paper does not conform to APA 6th edition requirements whatsoever. |
5 points out of 10: Appearance of final paper demonstrates the student’s limited ability to format the paper. There are significant errors in formatting and/or the total omission of major components of an APA 6th edition paper. They can include the omission of the cover page, abstract, and page numbers. Additionally the page has major formatting issues with spacing or paragraph formation. Font size might not conform to size requirements. The student also significantly writes too large or too short of and paper |
7 points out of 10: Research paper presents an above-average use of formatting skills. The paper has slight errors within the paper. This can include small errors or omissions with the cover page, abstract, page number, and headers. There could be also slight formatting issues with the document spacing or the font Additionally the paper might slightly exceed or undershoot the specific number of required written pages for the assignment. |
10 points: Student provides a high-caliber, formatted paper. This includes an APA 6th edition cover page, abstract, page number, headers and is double spaced in 12’ Times Roman Font. Additionally, the paper conforms to the specific number of required written pages and neither goes over or under the specified length of the paper. |
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The role of stress in autoimmune disorders
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