Genetic Drift among Amish Paper
Order ID 53563633773 Type Essay Writer Level Masters Style APA Sources/References 4 Perfect Number of Pages to Order 5-10 Pages Description/Paper Instructions
Genetic Drift among Amish Paper
https://www.youtube.com/watch?v=_eAJDQ_SgDk&feature=emb_title
Before you begin the assignment make sure you view the video “Gene Disorders Hit Amish Hard” and make sure you read this week’s PDF “Evolution and its Mechanisms”
Genetic Drift Webquest
Introduction
The Amish in the US began as a small group of Swiss-Germans that immigrated to the US in the 1700’s. Over the course of a few centuries they grew from a small founding population of 200 to a current population of more than 250,000. The most interesting thing about the Amish is that it’s a religious group that has remained culturally isolated and by extension, genetically isolated from the rest of the country. This genetic isolation from other humans has lead to an unprecedented amount of genetic disorders among the Amish.
Physicians were initially exposed to the genetic problems plaguing the Amish in the 1960’s. When the Amish began to reach out to the medial community doctors discovered that there were an unusual number of rare genetic diseases. One of these visible and rare genetic disease was called Ellis-Van Creveld syndrome. What was surprising to medical geneticists was not the presence of the rare genetic disease but rather how many Amish had the disease in the first place. Basically, the Amish in Lancaster County, Pennsylvania had more cases of Ellis-Van Creveld syndrome than all other human in the world combined! What was even more surprising was the fact that there was not just one rare genetic disease but rather dozens of rare genetic disease (In this context, rare genetic disease means that there may be less than 150 humans in the planet having the disease). Even more unfortunate is the fact that there are hundreds of other genetic disease associated with the Amish.
The big question that the Amish wanted to know was, why do they seem to have an unusual share of genetic disease when compared to the non-Amish and how do they stop those genetic disease in the first place!
What you are doing
Your task will be to investigate a rare genetic disorder found among the Amish and to use evolutionary theory to both, help you understand why genetic disease can become common among isolated populations and to see how evolutionary theory can assist in curbing prevalence of genetic disease.
Before you begin your task make sure you do the following things.
Read lecture notes on evolution. Especially the ones pertaining to Genetic drift.
Watch video on Amish genetic diseases.
What you need to do
Before you begin this assignment, I recommend that you clearly understand what evolution is (a change in allele frequency from one generation to the next). Make sure you use the information provided and give me informed ideas that are based on your understanding of the subject matter. For this assignment you will have to answer the following items:
Pick and a rare genetic disorder that is common among the Amish and tell me how common the disease is around the world vs among the Amish? Give me estimated percentage of afflicted individuals! (I don’t need to know details of the genetic disease just its name). The important idea is to understand why disease associated alleles are found in high frequencies in the first place!
Explain in evolutionary terms why the genetic disorder that you investigated is found in unusually high frequencies among the Amish in the first place. You will need to give me one evolutionary mechanism that can specifically explain the Amish issue. Make sure you name the evolutionary mechanism and give a quick explanation of how the evolutionary mechanism works.
Explain how the Amish might be able to curtail the incidence of your chosen genetic diseases using evolutionary knowledge. You will need to give me one evolutionary mechanism that would be able to fix the Amish dilemma. Make sure name the evolutionary mechanism and give a quick explanation of how the evolutionary mechanism would be able to work.
Lastly, remember to cite all your work!
RUBRIC
QUALITY OF RESPONSE NO RESPONSE POOR / UNSATISFACTORY SATISFACTORY GOOD EXCELLENT Content (worth a maximum of 50% of the total points) Zero points: Student failed to submit the final paper. 20 points out of 50: The essay illustrates poor understanding of the relevant material by failing to address or incorrectly addressing the relevant content; failing to identify or inaccurately explaining/defining key concepts/ideas; ignoring or incorrectly explaining key points/claims and the reasoning behind them; and/or incorrectly or inappropriately using terminology; and elements of the response are lacking. 30 points out of 50: The essay illustrates a rudimentary understanding of the relevant material by mentioning but not full explaining the relevant content; identifying some of the key concepts/ideas though failing to fully or accurately explain many of them; using terminology, though sometimes inaccurately or inappropriately; and/or incorporating some key claims/points but failing to explain the reasoning behind them or doing so inaccurately. Elements of the required response may also be lacking. 40 points out of 50: The essay illustrates solid understanding of the relevant material by correctly addressing most of the relevant content; identifying and explaining most of the key concepts/ideas; using correct terminology; explaining the reasoning behind most of the key points/claims; and/or where necessary or useful, substantiating some points with accurate examples. The answer is complete. 50 points: The essay illustrates exemplary understanding of the relevant material by thoroughly and correctly addressing the relevant content; identifying and explaining all of the key concepts/ideas; using correct terminology explaining the reasoning behind key points/claims and substantiating, as necessary/useful, points with several accurate and illuminating examples. No aspects of the required answer are missing. Use of Sources (worth a maximum of 20% of the total points). Zero points: Student failed to include citations and/or references. Or the student failed to submit a final paper. 5 out 20 points: Sources are seldom cited to support statements and/or format of citations are not recognizable as APA 6th Edition format. There are major errors in the formation of the references and citations. And/or there is a major reliance on highly questionable. The Student fails to provide an adequate synthesis of research collected for the paper. 10 out 20 points: References to scholarly sources are occasionally given; many statements seem unsubstantiated. Frequent errors in APA 6th Edition format, leaving the reader confused about the source of the information. There are significant errors of the formation in the references and citations. And/or there is a significant use of highly questionable sources. 15 out 20 points: Credible Scholarly sources are used effectively support claims and are, for the most part, clear and fairly represented. APA 6th Edition is used with only a few minor errors. There are minor errors in reference and/or citations. And/or there is some use of questionable sources. 20 points: Credible scholarly sources are used to give compelling evidence to support claims and are clearly and fairly represented. APA 6th Edition format is used accurately and consistently. The student uses above the maximum required references in the development of the assignment. Grammar (worth maximum of 20% of total points) Zero points: Student failed to submit the final paper. 5 points out of 20: The paper does not communicate ideas/points clearly due to inappropriate use of terminology and vague language; thoughts and sentences are disjointed or incomprehensible; organization lacking; and/or numerous grammatical, spelling/punctuation errors 10 points out 20: The paper is often unclear and difficult to follow due to some inappropriate terminology and/or vague language; ideas may be fragmented, wandering and/or repetitive; poor organization; and/or some grammatical, spelling, punctuation errors 15 points out of 20: The paper is mostly clear as a result of appropriate use of terminology and minimal vagueness; no tangents and no repetition; fairly good organization; almost perfect grammar, spelling, punctuation, and word usage. 20 points: The paper is clear, concise, and a pleasure to read as a result of appropriate and precise use of terminology; total coherence of thoughts and presentation and logical organization; and the essay is error free. Structure of the Paper (worth 10% of total points) Zero points: Student failed to submit the final paper. 3 points out of 10: Student needs to develop better formatting skills. The paper omits significant structural elements required for and APA 6th edition paper. Formatting of the paper has major flaws. The paper does not conform to APA 6th edition requirements whatsoever. 5 points out of 10: Appearance of final paper demonstrates the student’s limited ability to format the paper. There are significant errors in formatting and/or the total omission of major components of an APA 6th edition paper. They can include the omission of the cover page, abstract, and page numbers. Additionally the page has major formatting issues with spacing or paragraph formation. Font size might not conform to size requirements. The student also significantly writes too large or too short of and paper 7 points out of 10: Research paper presents an above-average use of formatting skills. The paper has slight errors within the paper. This can include small errors or omissions with the cover page, abstract, page number, and headers. There could be also slight formatting issues with the document spacing or the font Additionally the paper might slightly exceed or undershoot the specific number of required written pages for the assignment. 10 points: Student provides a high-caliber, formatted paper. This includes an APA 6th edition cover page, abstract, page number, headers and is double spaced in 12’ Times Roman Font. Additionally, the paper conforms to the specific number of required written pages and neither goes over or under the specified length of the paper. GET THIS PROJECT NOW BY CLICKING ON THIS LINK TO PLACE THE ORDER
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