The Carbonic Anhydrase Essay Assignment
Order ID 53563633773 Type Essay Writer Level Masters Style APA Sources/References 4 Perfect Number of Pages to Order 5-10 Pages
Description/Paper Instructions
there is a step 1 include in the files will be uploaded and all instructions of step four needed to be followed and need to be done as directed the attached one is the required part .
6) General Structural Features of the Enzyme: (if you cannot find all of the information for human enzyme, it is OK to describe from other organisms) Size of the protein.
Primary structure = amino acid sequence
Secondary structures such as alpha helices and beta sheets info
Special features such as active site information, binding site, cofactor or prosthetic groups binding sites, or any other special features from tertiary structure and folding
Quaternary structure (if it is monomer, dimer, trimer, or tetramer, in different organisms) and any other structural details you find for each subunit
Is there any “homology” (= similarities) described for different organisms
Any post-translational modification the protein undergoes
Information from crystal structure studies by authors
Now find references and find the pictures of the enzyme structure. Include them in the report, continue to give figure numbers, description (legend) and reference.7) Physiological/Biological Function of the Enzyme:
• Describe the general function of the enzyme = in which metabolic pathways the reaction catalyzed by the enzyme involved, or what roles does it play in the organisms = How is it useful for the organism
• Make sure you have read the publications about this, not just what the database directly gives and include all the additional information you found from these publications.8) Inhibitors (and activators if available): (you can find this in Brenda site and for details read the publications listed in the Brenda site)
• Which are the inhibitors (and also activators) for your enzyme? (You can first get it from the Brenda site, and then look for details from the references the site lists). List all the ones you find.
• Are these activators and inhibitors physiologically generated within the organism, or are they external ones?
• What is the mechanism by which they activate or inhibit? (for at least one inhibitor and one activator you must describe in detail)
• For the inhibitors (at least one inhibitor) what are the kinetics data (Ki Inhibitor constant, IC50 = What is the conc for 50% inhibition).
• What are the consequences of inhibition or activation.9) Medical, diagnostic, or industrial or other types of applications:
Describe any of these applications you find from the databases and the references that are listed in the database, to find enough information.
Which applications
Why or how is the enzyme involved in these applications.10) Mutations or other impairments, and Diseases caused by mutations, impairments or deficiencies of the enzyme:
• What types of mutations or impairments or why the deficiencies are caused
• What happens to the enzyme due to the above
• What are the consequences?11) Conclusions: (just create this title; you will work on the writing part for final step of the project)
12) Acknowledgements: (just create this title, but you will work on this for next step of the project)
This the required part please step one is only required to have an idea only.
RUBRIC
QUALITY OF RESPONSE NO RESPONSE POOR / UNSATISFACTORY SATISFACTORY GOOD EXCELLENT Content (worth a maximum of 50% of the total points) Zero points: Student failed to submit the final paper. 20 points out of 50: The essay illustrates poor understanding of the relevant material by failing to address or incorrectly addressing the relevant content; failing to identify or inaccurately explaining/defining key concepts/ideas; ignoring or incorrectly explaining key points/claims and the reasoning behind them; and/or incorrectly or inappropriately using terminology; and elements of the response are lacking. 30 points out of 50: The essay illustrates a rudimentary understanding of the relevant material by mentioning but not full explaining the relevant content; identifying some of the key concepts/ideas though failing to fully or accurately explain many of them; using terminology, though sometimes inaccurately or inappropriately; and/or incorporating some key claims/points but failing to explain the reasoning behind them or doing so inaccurately. Elements of the required response may also be lacking. 40 points out of 50: The essay illustrates solid understanding of the relevant material by correctly addressing most of the relevant content; identifying and explaining most of the key concepts/ideas; using correct terminology; explaining the reasoning behind most of the key points/claims; and/or where necessary or useful, substantiating some points with accurate examples. The answer is complete. 50 points: The essay illustrates exemplary understanding of the relevant material by thoroughly and correctly addressing the relevant content; identifying and explaining all of the key concepts/ideas; using correct terminology explaining the reasoning behind key points/claims and substantiating, as necessary/useful, points with several accurate and illuminating examples. No aspects of the required answer are missing. Use of Sources (worth a maximum of 20% of the total points). Zero points: Student failed to include citations and/or references. Or the student failed to submit a final paper. 5 out 20 points: Sources are seldom cited to support statements and/or format of citations are not recognizable as APA 6th Edition format. There are major errors in the formation of the references and citations. And/or there is a major reliance on highly questionable. The Student fails to provide an adequate synthesis of research collected for the paper. 10 out 20 points: References to scholarly sources are occasionally given; many statements seem unsubstantiated. Frequent errors in APA 6th Edition format, leaving the reader confused about the source of the information. There are significant errors of the formation in the references and citations. And/or there is a significant use of highly questionable sources. 15 out 20 points: Credible Scholarly sources are used effectively support claims and are, for the most part, clear and fairly represented. APA 6th Edition is used with only a few minor errors. There are minor errors in reference and/or citations. And/or there is some use of questionable sources. 20 points: Credible scholarly sources are used to give compelling evidence to support claims and are clearly and fairly represented. APA 6th Edition format is used accurately and consistently. The student uses above the maximum required references in the development of the assignment. Grammar (worth maximum of 20% of total points) Zero points: Student failed to submit the final paper. 5 points out of 20: The paper does not communicate ideas/points clearly due to inappropriate use of terminology and vague language; thoughts and sentences are disjointed or incomprehensible; organization lacking; and/or numerous grammatical, spelling/punctuation errors 10 points out 20: The paper is often unclear and difficult to follow due to some inappropriate terminology and/or vague language; ideas may be fragmented, wandering and/or repetitive; poor organization; and/or some grammatical, spelling, punctuation errors 15 points out of 20: The paper is mostly clear as a result of appropriate use of terminology and minimal vagueness; no tangents and no repetition; fairly good organization; almost perfect grammar, spelling, punctuation, and word usage. 20 points: The paper is clear, concise, and a pleasure to read as a result of appropriate and precise use of terminology; total coherence of thoughts and presentation and logical organization; and the essay is error free. Structure of the Paper (worth 10% of total points) Zero points: Student failed to submit the final paper. 3 points out of 10: Student needs to develop better formatting skills. The paper omits significant structural elements required for and APA 6th edition paper. Formatting of the paper has major flaws. The paper does not conform to APA 6th edition requirements whatsoever. 5 points out of 10: Appearance of final paper demonstrates the student’s limited ability to format the paper. There are significant errors in formatting and/or the total omission of major components of an APA 6th edition paper. They can include the omission of the cover page, abstract, and page numbers. Additionally the page has major formatting issues with spacing or paragraph formation. Font size might not conform to size requirements. The student also significantly writes too large or too short of and paper 7 points out of 10: Research paper presents an above-average use of formatting skills. The paper has slight errors within the paper. This can include small errors or omissions with the cover page, abstract, page number, and headers. There could be also slight formatting issues with the document spacing or the font Additionally the paper might slightly exceed or undershoot the specific number of required written pages for the assignment. 10 points: Student provides a high-caliber, formatted paper. This includes an APA 6th edition cover page, abstract, page number, headers and is double spaced in 12’ Times Roman Font. Additionally, the paper conforms to the specific number of required written pages and neither goes over or under the specified length of the paper. GET THIS PROJECT NOW BY CLICKING ON THIS LINK TO PLACE THE ORDER
CLICK ON THE LINK HERE: https://www.perfectacademic.com/orders/ordernow
Also, you can place the order at www.collegepaper.us/orders/ordernow / www.phdwriters.us/orders/ordernow
Do You Have Any Other Essay/Assignment/Class Project/Homework Related to this? Click Here Now [CLICK ME] and Have It Done by Our PhD Qualified Writers!!