Gene modification in biopharmaceuticals production.
Order ID |
53563633773 |
Type |
Essay |
Writer Level |
Masters |
Style |
APA |
Sources/References |
4 |
Perfect Number of Pages to Order |
5-10 Pages |
Description/Paper Instructions
Gene modification in biopharmaceuticals production.
Gene modification refers to the process of altering an organism’s genetic material to create a desired trait. In biopharmaceuticals production, gene modification is used to engineer microorganisms such as bacteria, yeast, and fungi to produce therapeutic proteins. These proteins can then be purified and used as drugs to treat various diseases.
The process of gene modification involves several steps, including:
Identification of the gene of interest: The first step is to identify the gene that codes for the therapeutic protein of interest. This gene is then isolated from the organism and cloned into a vector.
Cloning: The next step is to clone the gene of interest into a vector. Vectors are genetic elements that can be used to transfer genetic material from one organism to another. The most commonly used vectors in biopharmaceutical production are plasmids.
Transformation: The next step is to introduce the vector into the host organism. This can be done through a process called transformation, where the vector is physically introduced into the host cell. Alternatively, the vector can be introduced into the host through electroporation, a process where an electric field is used to open the cell membrane and allow the vector to enter.
Expression: Once the vector is introduced into the host organism, the gene of interest is expressed, meaning it is translated into a functional protein. The host organism is then cultured in a suitable environment to promote growth and protein production.
Purification: The final step is to purify the therapeutic protein produced by the host organism. This is typically done through a series of filtration and separation steps to remove impurities and contaminants.
Gene modification in biopharmaceuticals production has several advantages. First, it allows for the production of large quantities of a specific protein, making it cost-effective and efficient. Additionally, gene modification allows for the production of proteins that are not easily obtained through traditional methods, such as animal-derived products.
Gene modification also allows for the production of highly purified and well-characterized therapeutic proteins, reducing the risk of adverse reactions in patients. Furthermore, gene modification can be used to produce proteins with specific modifications that improve their activity, stability, or specificity.
Despite these advantages, gene modification in biopharmaceuticals production also has some challenges. For example, the process of gene modification can be time-consuming and expensive, requiring significant investment in research and development. Additionally, there is a risk of unintended consequences, such as the production of harmful proteins or the development of resistance in the host organism.
In conclusion, gene modification is a crucial tool in the production of biopharmaceuticals, allowing for the efficient and cost-effective production of therapeutic proteins. Despite some challenges, the advantages of gene modification have led to its widespread use in biopharmaceuticals production, and it continues to play a crucial role in the development of new and effective treatments for a wide range of diseases.
RUBRIC
QUALITY OF RESPONSE |
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POOR / UNSATISFACTORY |
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EXCELLENT |
Content (worth a maximum of 50% of the total points) |
Zero points: Student failed to submit the final paper. |
20 points out of 50: The essay illustrates poor understanding of the relevant material by failing to address or incorrectly addressing the relevant content; failing to identify or inaccurately explaining/defining key concepts/ideas; ignoring or incorrectly explaining key points/claims and the reasoning behind them; and/or incorrectly or inappropriately using terminology; and elements of the response are lacking. |
30 points out of 50: The essay illustrates a rudimentary understanding of the relevant material by mentioning but not full explaining the relevant content; identifying some of the key concepts/ideas though failing to fully or accurately explain many of them; using terminology, though sometimes inaccurately or inappropriately; and/or incorporating some key claims/points but failing to explain the reasoning behind them or doing so inaccurately. Elements of the required response may also be lacking. |
40 points out of 50: The essay illustrates solid understanding of the relevant material by correctly addressing most of the relevant content; identifying and explaining most of the key concepts/ideas; using correct terminology; explaining the reasoning behind most of the key points/claims; and/or where necessary or useful, substantiating some points with accurate examples. The answer is complete. |
50 points: The essay illustrates exemplary understanding of the relevant material by thoroughly and correctly addressing the relevant content; identifying and explaining all of the key concepts/ideas; using correct terminology explaining the reasoning behind key points/claims and substantiating, as necessary/useful, points with several accurate and illuminating examples. No aspects of the required answer are missing. |
Use of Sources (worth a maximum of 20% of the total points). |
Zero points: Student failed to include citations and/or references. Or the student failed to submit a final paper. |
5 out 20 points: Sources are seldom cited to support statements and/or format of citations are not recognizable as APA 6th Edition format. There are major errors in the formation of the references and citations. And/or there is a major reliance on highly questionable. The Student fails to provide an adequate synthesis of research collected for the paper. |
10 out 20 points: References to scholarly sources are occasionally given; many statements seem unsubstantiated. Frequent errors in APA 6th Edition format, leaving the reader confused about the source of the information. There are significant errors of the formation in the references and citations. And/or there is a significant use of highly questionable sources. |
15 out 20 points: Credible Scholarly sources are used effectively support claims and are, for the most part, clear and fairly represented. APA 6th Edition is used with only a few minor errors. There are minor errors in reference and/or citations. And/or there is some use of questionable sources. |
20 points: Credible scholarly sources are used to give compelling evidence to support claims and are clearly and fairly represented. APA 6th Edition format is used accurately and consistently. The student uses above the maximum required references in the development of the assignment. |
Grammar (worth maximum of 20% of total points) |
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5 points out of 20: The paper does not communicate ideas/points clearly due to inappropriate use of terminology and vague language; thoughts and sentences are disjointed or incomprehensible; organization lacking; and/or numerous grammatical, spelling/punctuation errors |
10 points out 20: The paper is often unclear and difficult to follow due to some inappropriate terminology and/or vague language; ideas may be fragmented, wandering and/or repetitive; poor organization; and/or some grammatical, spelling, punctuation errors |
15 points out of 20: The paper is mostly clear as a result of appropriate use of terminology and minimal vagueness; no tangents and no repetition; fairly good organization; almost perfect grammar, spelling, punctuation, and word usage. |
20 points: The paper is clear, concise, and a pleasure to read as a result of appropriate and precise use of terminology; total coherence of thoughts and presentation and logical organization; and the essay is error free. |
Structure of the Paper (worth 10% of total points) |
Zero points: Student failed to submit the final paper. |
3 points out of 10: Student needs to develop better formatting skills. The paper omits significant structural elements required for and APA 6th edition paper. Formatting of the paper has major flaws. The paper does not conform to APA 6th edition requirements whatsoever. |
5 points out of 10: Appearance of final paper demonstrates the student’s limited ability to format the paper. There are significant errors in formatting and/or the total omission of major components of an APA 6th edition paper. They can include the omission of the cover page, abstract, and page numbers. Additionally the page has major formatting issues with spacing or paragraph formation. Font size might not conform to size requirements. The student also significantly writes too large or too short of and paper |
7 points out of 10: Research paper presents an above-average use of formatting skills. The paper has slight errors within the paper. This can include small errors or omissions with the cover page, abstract, page number, and headers. There could be also slight formatting issues with the document spacing or the font Additionally the paper might slightly exceed or undershoot the specific number of required written pages for the assignment. |
10 points: Student provides a high-caliber, formatted paper. This includes an APA 6th edition cover page, abstract, page number, headers and is double spaced in 12’ Times Roman Font. Additionally, the paper conforms to the specific number of required written pages and neither goes over or under the specified length of the paper. |
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Gene modification in biopharmaceuticals production.
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